Effects of Thyroid Function on Hemostasis, Coagulation, and Fibrinolysis: A Mendelian Randomization Study.

doi:10.1089/thy.2021.0055

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Article

Effects of Thyroid Function on Hemostasis, Coagulation, and Fibrinolysis: A Mendelian Randomization Study.

Thyroid : official journal of the American Thyroid Association - 1 Sept 2021

Ellervik Christina, Mora Samia, Kuś Aleksander, Åsvold Bjørn, Marouli Eirini, Deloukas Panos, Sterenborg Rosalie B T M, Teumer Alexander, Burgess Stephen, Sabater-Lleal Maria, Huffman Jennifer, Johnson Andrew D, Trégouet David-Alexandre, Smith Nicolas L, Medici Marco, DeVries Paul S, Chasman Daniel I, Kjaergaard Alisa D

Abstract excerpt

Background: Untreated hypothyroidism is associated with acquired von Willebrand syndrome, and hyperthyroidism is associated with increased thrombosis risk. However, the causal effects of thyroid function on hemostasis, coagulation, and fibrinolysis are unknown. Methods: In a two-sample Mendelian randomization (MR) study with genome-wide association variants, we assessed causality of genetically predicted...

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Identifiers

PMID: 34210154
DOI: 10.1089/thy.2021.0055
PMCID: PMC8558080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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