Article
NOD2 polymorphism predicts response to treatment in Crohn's disease--first steps to a personalized therapy.
Digestive diseases and sciences - 1 Apr 2012
Niess Jan Hendrik, Klaus Jochen, Stephani Johannes, Pflüger Carolin, Degenkolb Nadine, Spaniol Ulrike, Mayer Benjamin, Lahr Georgia, von Boyen Georg B T
Abstract excerpt
BACKGROUND AND AIMS: Great efforts have been made to predict disease behavior over time and the response to treatment in Crohn's disease (CD). Such understanding could personalize therapy. Early introduction of more aggressive therapies to patients at high risk and no introduction of predictable refractory treatments could become possible. We hence tested the influence of the NOD2 carrier status on treatment...
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