Article
Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk.
Molecular carcinogenesis - 1 Oct 2021
Wang Haijiao, Liu Hongliang, Zhao Lingling, Luo Sheng, Akinyemiju Tomi, Hwang Shelley, Yue Ying, Wei Qingyi
Abstract excerpt
Forkhead box class O (FOXO) transcription factors play a pivotal role in regulating a variety of biological processes, including organismal development, cell signaling, cell metabolism, and tumorigenesis. Therefore, we hypothesize that genetic variants in FOXO pathway genes are associated with breast cancer (BC) risk. To test this hypothesis, we conducted a large meta-analysis using 14 published genome-wide...
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