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Article

iTARGEX analysis of yeast deletome reveals novel regulators of transcriptional buffering in S phase and protein turnover.

Nucleic acids research - 21 Jul 2021

Huang Jia-Hsin, Liao You-Rou, Lin Tzu-Chieh, Tsai Cheng-Hung, Lai Wei-Yun, Chou Yang-Kai, Leu Jun-Yi, Tsai Huai-Kuang, Kao Cheng-Fu

Abstract excerpt

Integrating omics data with quantification of biological traits provides unparalleled opportunities for discovery of genetic regulators by in silico inference. However, current approaches to analyze genetic-perturbation screens are limited by their reliance on annotation libraries for prioritization of hits and subsequent targeted experimentation. Here, we present iTARGEX (identification of Trait-Associated...

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PMID: 34197604
DOI: 10.1093/nar/gkab555
PMCID: PMC8287957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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