Article
Mast Cells Modulate Antigen-Specific CD8+ T Cell Activation During LCMV Infection.
Frontiers in immunology - 1 Jan 2021
Hackler Yana, Siebenhaar Frank, Löhning Max, Maurer Marcus, Muñoz Melba
Abstract excerpt
Mast cells (MCs), strategically localized at mucosal surfaces, provide first-line defense against pathogens and shape innate and adaptive immune responses. Recent studies have shown that MCs are involved in pathogenic responses to several viruses including herpes simplex viruses, dengue virus, vaccinia virus and influenza virus. However, the underlying mechanisms of MCs in the activation of CD8+ T cells during...
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