Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of TLR7 agonist R848 treatment on mast cell phenotype and activity.

Cellular immunology - 1 Jan 2021

Agier Justyna, Brzezińska-Błaszczyk Ewa, Witczak Piotr, Kozłowska Elżbieta, Żelechowska Paulina

Abstract excerpt

Bearing in mind that mast cell contribution to viral clearance is still not fully understood, in this study, we evaluated the effect of Toll-like receptor (TLR)7 viral single-stranded ribonucleic acid (ssRNA) mimic ligand, namely resiquimod (R)848, on mast cell phenotype and activity. We demonstrated that rat peritoneal mast cells exhibit surface and intracellular expression of ssRNA-specific TLR7 molecule, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Rats, Wistar
Share to Imidazoles
Share to Interferon gamma Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mast Cells

Share to Receptor, Interferon alpha-beta

Share to Receptors, IgE

Share to Receptors, Interferon

Share to Toll-Like Receptor 7

Source

Identifiers

PMID: 33158544
DOI: 10.1016/j.cellimm.2020.104241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of TLR7 agonist R848 treatment on mast cell phenotype and activity.PMID 33158544Read ↗

Mast cells: beyond IgE.Semantic proximity Read ↗

Differential TLR-ERK1/2 activity promotes viral ssRNA and dsRNA mimic-induced dysregulated immunity in macrophagesSemantic proximity Read ↗

Novel Identified Receptors on Mast CellsSemantic proximity Read ↗

Mast Cells Modulate Antigen-Specific CD8+ T Cell Activation During LCMV Infection.Semantic proximity Read ↗

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interactionSemantic proximity Read ↗

Traditional Chinese medicine andrographolide sulfonate alleviates airway inflammation by supressing TRL3-TRIF in mice post respiratory syncytial virus infectionSemantic proximity Read ↗

Respiratory syncytial virus promoted the differentiation of Th17 cells in airway microenvironment through activation of Notch-1/Delta3Semantic proximity Read ↗

Targeting Toll-like receptors with small molecule agentsSemantic proximity Read ↗

Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptorSemantic proximity Read ↗

Metadichol® induced expression of the TLR family of receptors in PBMCsSemantic proximity Read ↗

Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide.Semantic proximity Read ↗

Targeting Toll-like Receptor 2: synthetic diacylated lipopeptides polarize equine macrophages towards a pro-inflammatory phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.