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Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation

29 Jun 2021

Abstract excerpt

Mitochondrial function is required for brain energy homeostasis and neuroadaptation. Recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological characteristics within the nucleus accumbens (NAc). Further, mitochondria are differentially regulated by cocaine in dopamine receptor-1 containing medium spiny neurons (D1-MSNs) vs dopamine receptor-2 (D2)-MSNs. However, there is little...

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PMID: 34187517
DOI: 10.1186/s13041-021-00800-y

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