Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis

31 Jan 2020

Abstract excerpt

Cancer metastasis is largely incurable and accounts for 90% of breast cancer deaths, especially for the aggressive basal-like or triple negative breast cancer (TNBC). Combining patient database analyses and functional studies, we examined the association of integrin family members with clinical outcomes as well as their connection with previously identified microRNA regulators of metastasis, such as miR-206 that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34179312
DOI: 10.1016/j.gendis.2020.01.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasisPMID 34179312Read ↗

<i>ITGA2</i> is a target of miR-206 promoting cancer stemness and lung metastasis through enhanced <i>ACLY</i> and <i>CCND1</i> expression in triple negative breast cancerSemantic proximity Read ↗

Regulation and Functions of α6-Integrin (CD49f) in Cancer BiologySemantic proximity Read ↗

ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer modelsSemantic proximity Read ↗

In silico transcriptomic mapping of integrins and immune activation in Basal-like and HER2+ breast cancerSemantic proximity Read ↗

Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer CellsSemantic proximity Read ↗

Integrins regulate stemness in solid tumor: an emerging therapeutic target.Semantic proximity Read ↗

A Bioinformatic Investigation into the Role of ITGB1 in Cancer Prognosis and Therapeutic ResistanceSemantic proximity Read ↗

Integrin α6 (CD49f), The Microenvironment and Cancer Stem CellsSemantic proximity Read ↗

G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer CellsSemantic proximity Read ↗

Integrating Single-cell and Machine Learning with Experimental Validation Reveals FASN Conferring Breast Cancer Stem cell-like Properties: Therapeutic Insights and Prognostic ImplicationsSemantic proximity Read ↗

A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and MetastasisSemantic proximity Read ↗

ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.