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Integrin α6 (CD49f), The Microenvironment and Cancer Stem Cells

5 Oct 2018

Abstract excerpt

Cancer is a highly prevalent and potentially terminal disease that affects millions of individuals worldwide. Here, we review the literature exploring the intricacies of stem cells bearing tumorigenic characteristics and collect evidence demonstrating the importance of integrin α6 (ITGA6, also known as CD49f) in cancer stem cell (CSC) activity. ITGA6 is commonly used to identify CSC populations in various tissues...

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PMID: 30280675
DOI: 10.2174/1574888x13666181002151330

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