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Article

Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis?

Arthritis care & research - 1 May 2012

Joshi Reeti, Reveille John D, Brown Matthew A, Weisman Michael H, Ward Michael M, Gensler Lianne S, Wordsworth B Paul, Evans David M, Assassi Shervin

Abstract excerpt

OBJECTIVE: Several genetic risk variants for ankylosing spondylitis (AS) have been identified in genome-wide association studies. Our objective was to examine whether familial AS cases have a higher genetic load of these susceptibility variants. METHODS: Overall, 502 AS patients were examined, consisting of 312 patients who had first-degree relatives (FDRs) with AS (familial) and 190 patients who had no FDRs with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spondylitis, Ankylosing

Source

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Identifiers

PMID: 22231927
DOI: 10.1002/acr.21601
PMCID: PMC3335985

Genes

ANTXR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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