Article
PHENSIM: Phenotype Simulator.
PLoS computational biology - 1 Jun 2021
Alaimo Salvatore, Rapicavoli Rosaria Valentina, Marceca Gioacchino P, La Ferlita Alessandro, Serebrennikova Oksana B, Tsichlis Philip N, Mishra Bud, Pulvirenti Alfredo, Ferro Alfredo
Abstract excerpt
Despite the unprecedented growth in our understanding of cell biology, it still remains challenging to connect it to experimental data obtained with cells and tissues' physiopathological status under precise circumstances. This knowledge gap often results in difficulties in designing validation experiments, which are usually labor-intensive, expensive to perform, and hard to interpret. Here we propose PHENSIM, a...
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