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Genetic Signatures From RNA Sequencing of Pediatric Localized Scleroderma Skin

7 Jun 2021

Abstract excerpt

The purpose of this study was to explore the skin transcriptional profile in pediatric localized scleroderma (LS) to provide a better understanding of the altered immune and fibrotic pathways promoting disease. LS is a progressive disease of the skin and underlying tissue that causes significant functional disability and disfigurement, especially in developing children. RNA sequencing (RNAseq) technology allows...

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PMID: 34164359
DOI: 10.3389/fped.2021.669116

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