Article

Identification of fibroinflammatory and fibrotic transcriptomic subsets of human sclerotic cutaneous chronic graft-versus-host disease

2022-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Cutaneous sclerotic chronic graft-versus-host disease (cGVHD) is a common and highly morbid complication of allogeneic hematopoietic stem cell transplantation (HSCT). We identified genes that are significantly upregulated in the skin of sclerotic cGVHD patients (n = 17) compared to HSCT patients without sclerotic cGVHD (n = 9) by bulk RNA sequencing. This revealed two transcriptomic groups of aff...

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Literature Corpus work: 3538b604-20ae-5036-9e81-b38b9f38faa2
DOI: 10.1101/2022.12.07.22283119

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