Article
Transcriptomic Evaluation of Juvenile Localized Scleroderma Skin With Histologic and Clinical Correlation.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Oct 2021
Schutt Christina, Mirizio Emily, Salgado Claudia, Reyes-Mugica Miguel, Wang Xinjun, Chen Wei, Grunwaldt Lorelei, Schollaert Kaila L, Torok Kathryn S
Abstract excerpt
OBJECTIVE: Juvenile localized scleroderma (LS) is an autoimmune disease of the skin whose pathogenesis is not well understood due to the rarity of the disease. This study was undertaken to determine the skin transcriptome in skin biopsy tissue from children with juvenile LS compared to pediatric healthy controls, with identification of significant molecular targets using RNA sequencing (RNA-Seq). In this study,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.