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Article

DNA methylation patterns in juvenile systemic sclerosis and localized scleroderma.

Clinical immunology (Orlando, Fla.) - 1 Jul 2021

Coit Patrick, Schollaert Kaila L, Mirizio Emily M, Torok Kathryn S, Sawalha Amr H

Abstract excerpt

Scleroderma refers to a group of chronic fibrotic immune-mediated diseases of unknown etiology. Characterizing epigenetic changes in childhood-onset scleroderma, systemic sclerosis or localized scleroderma, has not been previously performed. The aim of this study was to assess DNA methylation differences and similarities between juvenile systemic sclerosis (jSSc) and juvenile localized scleroderma (jLS) compared...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33992755
DOI: 10.1016/j.clim.2021.108756
PMCID: PMC8206011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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