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Article

TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

23 Jun 2021

Abstract excerpt

Abstract Testicular development and function rely on interactions between somatic cells and the germline, but similar to other organs, regenerative capacity declines in aging and disease. Whether the adult testis maintains a reserve progenitor population remains uncertain. Here, we characterize a recently identified mouse testis interstitial population expressing the transcription factor Tcf21. We found that...

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PMID: 34162856
DOI: 10.1038/s41467-021-24130-8

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