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Identification of Rat Testicular Leydig Precursor Cells by Single-Cell-RNA-Sequence Analysis

15 Feb 2022

Abstract excerpt

Stem Leydig cells (SLCs) play a critical role in the development and maintenance of the adult Leydig cell (ALC) population. SLCs also are present in the adult testis. Their identification, characteristics, and regulation in the adult testis remain uncertain. Using single-cell RNA-seq, we found that the mesenchymal stromal population may be involved in ALC regeneration. Upon ALC elimination, a fraction of stromal...

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PMID: 35242757
DOI: 10.3389/fcell.2022.805249

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