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Article

Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal

6 Mar 2009

Abstract excerpt

Self-renewal and differentiation of spermatogonial stem cells (SSCs) provide the foundation for testis homeostasis, yet mechanisms that control their functions in mammals are poorly defined. We used microarray transcript profiling to identify specific genes whose expressions are augmented in the SSC-enriched Thy1(+) germ cell fraction of mouse pup testes. Comparisons of gene expression in the Thy1(+) germ cell...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

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PMID: 19270176
DOI: 10.1242/dev.032243

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