Article
Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study.
Brazilian journal of biology = Revista brasleira de biologia - 1 Jan 2021
Barbosa L M, Santiago M B, Moretto V T, Athanazio D, Takahashi D, Reis E G, Lopes M, Lemaire D, Reis M G
Abstract excerpt
Toll-like receptor 9 (TLR9) is an important component of the innate immune system and have been associated with several autoimmune diseases, such as Systemic Lupus Erythematosus (SLE). The aim of this study was to investigate polymorphisms in TLR9 gene in a Brazilian SLE patients group and their association with clinical manifestation, particularly Jaccoud's arthropathy (JA). We analyzed DNA samples from 204 SLE...
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