Article
Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus.
Tissue antigens - 1 Mar 2005
Hur J-W, Shin H D, Park B L, Kim L H, Kim S-Y, Bae S-C
Abstract excerpt
Mammalian Toll-like receptors (TLR) play an important role in both adaptive immunity and innate immunity. Genetic variations within TLR genes are known to be associated with a variety of inflammatory and infectious diseases. TLR9 is potentially associated with autoimmune diseases, because it participates in the production of pro-inflammatory cytokines and the maturation of dendritic cells. We investigated the...
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