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Article

TLR4 and TLR9 polymorphisms are not associated with either rheumatoid arthritis or systemic lupus erythematosus in Mexican patients.

Molecular biology reports - 1 Apr 2021

Aranda-Uribe Ivan Sammir, López-Vázquez Juan Carlos, Barbosa-Cobos Rosa Elda, Ramírez-Bello Julian

Abstract excerpt

Toll-like receptor (TLR)-mediated signaling pathways induce a proinflammatory microenvironment to eradicate pathogens. However, in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), TLRs can promote chronic inflammation. It has been shown that some TLR4 and TLR9 single nucleotide polymorphisms (SNPs) are risk factors for RA and SLE, but these findings have not been replicated in all populations;...

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Identifiers

PMID: 33939072
DOI: 10.1007/s11033-021-06371-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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