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Article

High Rates of Ultraviolet-Signature Mutations in Squamous Cell Carcinomas of the Parotid Gland and Prognostic Implications.

Head and neck pathology - 1 Mar 2022

Fishbach Shira, Steinhardt George, Zhen Chao Jie, Puranik Rutika, Segal Jeremy P, Cipriani Nicole A

Abstract excerpt

In the absence of clear pathologic differences, clinical history may differentiate potential primary parotid squamous cell carcinomas (SCC) from metastases. The presence of an ultraviolet (UV) signature can distinguish between tumors of cutaneous and non-cutaneous origin. This study aimed to investigate rates of UV signature mutations in squamous cell carcinomas of the parotid gland as well as differences in...

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Identifiers

PMID: 34160783
DOI: 10.1007/s12105-021-01349-x
PMCID: PMC9018939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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