Article
The molecular landscape of well differentiated retroperitoneal liposarcoma.
The Journal of pathology - 1 Oct 2021
Tyler Robert, Dilworth Mark P, James Jonathan, Blakeway Daniel, Stockton Joanne D, Morton Dion G, Taniere Phillipe, Gourevitch David, Desai Anant, Beggs Andrew D
Abstract excerpt
Well differentiated liposarcoma (WD-LPS) is a relatively rare tumour, with fewer than 50 cases occurring per year in the UK. These tumours are both chemotherapy- and radiotherapy-resistant and present a significant treatment challenge requiring radical surgery. Little is known of the molecular landscape of these tumours and no current targets for molecular therapy exist. We aimed to carry out a comprehensive...
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