Article
Genomic landscape of liposarcoma.
Oncotarget - 15 Dec 2015
Kanojia Deepika, Nagata Yasunobu, Garg Manoj, Lee Dhong Hyun, Sato Aiko, Yoshida Kenichi, Sato Yusuke, Sanada Masashi, Mayakonda Anand, Bartenhagen Christoph, Klein Hans-Ulrich, Doan Ngan B, Said Jonathan W, Mohith S, Gunasekar Swetha, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Myklebost Ola, Yang Henry, Dugas Martin, Meza-Zepeda Leonardo A, Silberman Allan W, Forscher Charles, Tyner Jeffrey W, Ogawa Seishi, Koeffler H Phillip
Abstract excerpt
Liposarcoma (LPS) is the most common type of soft tissue sarcoma accounting for 20% of all adult sarcomas. Due to absence of clinically effective treatment options in inoperable situations and resistance to chemotherapeutics, a critical need exists to identify novel therapeutic targets. We analyzed LPS genomic landscape using SNP arrays, whole exome sequencing and targeted exome sequencing to uncover the genomic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.