Article
[Polygenetic pharmacogenomic strategies to identify drug sensitivity biomarkers].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Nov 2005
Nishiyama Masahiko
Abstract excerpt
Pharmacogenomics is a large-scale systematic approach using a variety of genomic technologies to discover drug response determinants and promote a better understanding of the genetic and molecular basis underlying variable drug response among patients. However, few critical prediction markers of drug response have been validated to date. Drug sensitivity is determined by multiple genes:drugs are often involved in...
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