Article
Potential associations between variants of genes encoding regulators of inflammation, and mediators of inflammation in type 2 diabetes and insulin resistance.
Journal of clinical pharmacy and therapeutics - 1 Oct 2021
Ozbayer Cansu, Kebapci Medine Nur, Kurt Hulyam, Colak Ertugrul, Gunes Hasan Veysi, Degirmenci Irfan
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Type 2 diabetes (T2DM) is a multigenic disease that develops with impaired β-cell function and insulin sensitivity and has a high prevalence worldwide. A cause often postulated for type 2 diabetes is chronic inflammation. It has been suggested that inflammatory regulators can inhibit insulin signal transduction and that inflammation is involved in insulin resistance (IR) and the...
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