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TNF-alpha −308G/A and −238G/A polymorphisms and its protein network associated with type 2 diabetes mellitus

26 May 2016

Abstract excerpt

Several reports document the role of tumor necrosis factor alpha ( TNF-α ) and lipid metabolism in the context of acute inflammation as a causative factor in obesity-associated insulin resistance and as one of the causative parameter of type 2 diabetes mellitus (T2DM). Our aim was to investigate the association between −308G/A and −238G/A polymorphisms located in the promoter region of the TNF-α gene in T2DM in...

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PMID: 28855812
DOI: 10.1016/j.sjbs.2016.05.012

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