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Article

Permethrin resistance in Aedes aegypti: Genomic variants that confer knockdown resistance, recovery, and death.

PLoS genetics - 1 Jun 2021

Saavedra-Rodriguez Karla, Campbell Corey L, Lozano Saul, Penilla-Navarro Patricia, Lopez-Solis Alma, Solis-Santoyo Francisco, Rodriguez Americo D, Perera Rushika, Black Iv William C

Abstract excerpt

Pyrethroids are one of the few classes of insecticides available to control Aedes aegypti, the major vector of dengue, chikungunya, and Zika viruses. Unfortunately, evolving mechanisms of pyrethroid resistance in mosquito populations threaten our ability to control disease outbreaks. Two common pyrethroid resistance mechanisms occur in Ae. aegypti: 1) knockdown resistance, which involves amino acid substitutions...

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Identifiers

PMID: 34138859
DOI: 10.1371/journal.pgen.1009606
PMCID: PMC8211209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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