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Combined target site (kdr) mutations play a primary role in highly pyrethroid resistant phenotypes of Aedes aegypti from Saudi Arabia.

Parasites & vectors - 27 Mar 2017

Al Nazawi Ashwaq M, Aqili Jabir, Alzahrani Mohammed, McCall Philip J, Weetman David

Abstract excerpt

BACKGROUND: Pyrethroid resistance is a threat to effective vector control of Aedes aegypti, the vector of dengue, Zika and other arboviruses, but there are many major knowledge gaps on the mechanisms of resistance. In Jeddah and Makkah, the principal dengue-endemic areas of Saudi Arabia, pyrethroids are used widely for Ae. aegypti control but information about resistance remains sparse, and the underlying genetic...

Topics

Aedes
Alleles
Animals
Dengue
Female
Fenitrothion
Genotype
Insecticide Resistance
Mosquito Vectors
Mutation
Nitriles
Permethrin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Phenylcarbamates

Piperonyl Butoxide

Pyrethrins

Saudi Arabia

Source

Open in PubMed Open full text

Identifiers

PMID: 28347352
DOI: 10.1186/s13071-017-2096-6
PMCID: PMC5368989

Genes

ABCB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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