Article
The GIMAP Family Proteins: An Incomplete Puzzle.
Frontiers in immunology - 1 Jan 2021
Limoges Marc-André, Cloutier Maryse, Nandi Madhuparna, Ilangumaran Subburaj, Ramanathan Sheela
Abstract excerpt
Overview: Long-term survival of T lymphocytes in quiescent state is essential to maintain their cell numbers in secondary lymphoid organs and in peripheral circulation. In the BioBreeding diabetes-prone strain of rats (BB-DP), loss of functional GIMAP5 (GTPase of the immune associated nucleotide binding protein 5) results in profound peripheral T lymphopenia. This discovery heralded the identification of a new...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
