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Exploring the role of ITGB6: fibrosis, cancer, and other diseases

21 Dec 2023

Abstract excerpt

Integrin β6 (ITGB6), a member of the integrin family of proteins, is only present in epithelial tissues and frequently associates with integrin subunit αv to form transmembrane heterodimers named integrin αvβ6. Importantly, ITGB6 determines αvβ6 expression and availability. In addition to being engaged in organ fibrosis, ITGB6 is also directly linked to the emergence of cancer, periodontitis, and several...

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PMID: 38127283
DOI: 10.1007/s10495-023-01921-6

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