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A DNA methylation-based liquid biopsy for triple-negative breast cancer

16 Jun 2021

Abstract excerpt

Abstract Here, we present a next-generation sequencing (NGS) methylation-based blood test called methylation DETEction of Circulating Tumour DNA (mDETECT) designed for the optimal detection and monitoring of metastatic triple-negative breast cancer (TNBC). Based on a highly multiplexed targeted sequencing approach, this assay incorporates features that offer superior performance and included 53 amplicons from 47...

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PMID: 34135468
DOI: 10.1038/s41698-021-00198-9

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