Article
Whole-exome sequencing reveals insights into genetic susceptibility to Congenital Zika Syndrome.
PLoS neglected tropical diseases - 1 Jun 2021
Borda Victor, da Silva Francisco Junior Ronaldo, Carvalho Joseane B, Morais Guilherme L, Duque Rossi Átila, Pezzuto Paula, Azevedo Girlene S, Schamber-Reis Bruno L, Portari Elyzabeth A, Melo Adriana, Moreira Maria Elisabeth L, Guida Letícia C, Cunha Daniela P, Gomes Leonardo, Vasconcelos Zilton F M, Faucz Fabio R, Tanuri Amilcar, Stratakis Constantine A, Aguiar Renato S, Cardoso Cynthia Chester, Vasconcelos Ana Tereza Ribeiro de
Abstract excerpt
Congenital Zika Syndrome (CZS) is a critical illness with a wide range of severity caused by Zika virus (ZIKV) infection during pregnancy. Life-threatening neurodevelopmental dysfunctions are among the most common phenotypes observed in affected newborns. Risk factors that contribute to susceptibility and response to ZIKV infection may be related to the virus itself, the environment, and maternal genetic...
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