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Article

Essential Role of CFAP53 in Sperm Flagellum Biogenesis

28 May 2021

Abstract excerpt

The sperm flagellum is essential for male fertility. Despite vigorous research progress toward understanding the pathogenesis of flagellum-related diseases, much remains unknown about the mechanisms underlying the flagellum biogenesis itself. Here, we show that the cilia and flagella associated protein 53 ( Cfap53 ) gene is predominantly expressed in testes, and it is essential for sperm flagellum biogenesis. The...

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PMID: 34124066
DOI: 10.3389/fcell.2021.676910

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