Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CFAP43-mediated intra-manchette transport is required for sperm head shaping and flagella formation

13 Oct 2020

Abstract excerpt

Mutation in CFAP43 leads to severe asthenozoospermia and multiple morphological abnormalities of the sperm flagellum (MMAF) in both human and mouse. Previous studies have shown that disruption of intra-manchette transport (IMT) caused failure of flagellum assembly and sperm head shaping. In a previous study, therefore, we postulated that disruption of IMT may contribute to the failure of sperm flagellum formation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33046149
DOI: 10.1017/s0967199420000556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CFAP43-mediated intra-manchette transport is required for sperm head shaping and flagella formationPMID 33046149Read ↗

Experimental and molecular support for Cfap70 as a causative gene of 'multiple morphological abnormalities of the flagella' with male infertility†.Semantic proximity Read ↗

Patients with MMAF induced by novel biallelic CFAP43 mutations have good fertility outcomes after intracytoplasmic sperm injection.Semantic proximity Read ↗

Essential role of CFAP53 in sperm flagellum biogenesisSemantic proximity Read ↗

Essential Role of CFAP53 in Sperm Flagellum BiogenesisSemantic proximity Read ↗

The cilia and flagella associated protein CFAP52 orchestrated with CFAP45 is required for sperm motility in miceSemantic proximity Read ↗

A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.Semantic proximity Read ↗

A novel recurrent mutation in CFAP47 causes male infertility with asthenoteratozoospermiaSemantic proximity Read ↗

Identification of CFAP52 as a novel diagnostic target of male infertility with defects of sperm head-tail connection and flagella developmentSemantic proximity Read ↗

Identification of CFAP52 as a novel diagnostic target of male infertility with defects of sperm head-tail connection and flagella developmentSemantic proximity Read ↗

Genetic causes of male infertility: snapshot on morphological abnormalities of the sperm flagellumSemantic proximity Read ↗

Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse.Semantic proximity Read ↗

Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.