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Article

Roles of IL-25 in Type 2 Inflammation and Autoimmune Pathogenesis

28 May 2021

Abstract excerpt

Interleukin-17E (IL-25) is a member of the IL-17 cytokine family that includes IL-17A to IL-17F. IL-17 family cytokines play a key role in host defense responses and inflammatory diseases. Compared with other IL-17 cytokine family members, IL-25 has relatively low sequence similarity to IL-17A and exhibits a distinct function from other IL-17 cytokines. IL-25 binds to its receptor composed of IL-17 receptor A...

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PMID: 34122457
DOI: 10.3389/fimmu.2021.691559

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