Article
Causal Effect of Adiposity Measures on Blood Pressure Traits in 2 Urban Swedish Cohorts: A Mendelian Randomization Study.
Journal of the American Heart Association - 6 Jul 2021
Giontella Alice, Lotta Luca A, Overton John D, Baras Aris, Minuz Pietro, Melander Olle, Gill Dipender, Fava Cristiano
Abstract excerpt
Background Different adiposity traits may be causally related to hypertension in different ways. By using genetic variants as randomly allocated proxies for studying the effect of modifying adiposity traits, the Mendelian randomization approach can be used to investigate this. Methods and Results In this study, we used 4 different genetic risk scores (GRS; GRS-BMI565, GRS-WHR324, GRS-VAT208, GRS-BF81) including...
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