Article
Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far?
Reviews in medical virology - 1 Nov 2021
Bouayad Abdellatif
Abstract excerpt
Modifications in HLA-I expression are found in many viral diseases. They represent one of the immune evasion strategies most widely used by viruses to block antigen presentation and NK cell response, and SARS-CoV-2 is no exception. These alterations result from a combination of virus-specific factors, genetically encoded mechanisms, and the status of host defences and range from loss or upregulation of HLA-I...
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