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Article

The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.

Immunological reviews - 1 Jul 2020

Ovsyannikova Inna G, Haralambieva Iana H, Crooke Stephen N, Poland Gregory A, Kennedy Richard B

Abstract excerpt

This article provides a review of studies evaluating the role of host (and viral) genetics (including variation in HLA genes) in the immune response to coronaviruses, as well as the clinical outcome of coronavirus-mediated disease. The initial sections focus on seasonal coronaviruses, SARS-CoV, and MERS-CoV. We then examine the state of the knowledge regarding genetic polymorphisms and SARS-CoV-2 and COVID-19....

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Source

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Identifiers

PMID: 32658335
DOI: 10.1111/imr.12897
PMCID: PMC7404857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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