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Evaluating causality of cellular senescence in non-alcoholic fatty liver disease

1 May 2021

Abstract excerpt

Cellular senescence is a state of irreversible cell cycle arrest that has important physiological functions. However, cellular senescence is also a hallmark of ageing and has been associated with several pathological conditions. A wide range of factors including genotoxic stress, mitogens and inflammatory cytokines can induce senescence. Phenotypically, senescent cells are characterised by short telomeres, an...

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PMID: 34113839
DOI: 10.1016/j.jhepr.2021.100301

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