Article
Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study.
BMC genomics - 9 Jun 2021
Hu Yao, Bien Stephanie A, Nishimura Katherine K, Haessler Jeffrey, Hodonsky Chani J, Baldassari Antoine R, Highland Heather M, Wang Zhe, Preuss Michael, Sitlani Colleen M, Wojcik Genevieve L, Tao Ran, Graff Mariaelisa, Huckins Laura M, Sun Quan, Chen Ming-Huei, Mousas Abdou, Auer Paul L, Lettre Guillaume, Tang Weihong, Qi Lihong, Thyagarajan Bharat, Buyske Steve, Fornage Myriam, Hindorff Lucia A, Li Yun, Lin Danyu, Reiner Alexander P, North Kari E, Loos Ruth J F, Raffield Laura M, Peters Ulrike, Avery Christy L, Kooperberg Charles
Abstract excerpt
BACKGROUND: Circulating white blood cell and platelet traits are clinically linked to various disease outcomes and differ across individuals and ancestry groups. Genetic factors play an important role in determining these traits and many loci have been identified. However, most of these findings were identified in populations of European ancestry (EA), with African Americans (AA), Hispanics/Latinos (HL), and...
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