Article
Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.
Cell - 17 Oct 2019
Peterson Roseann E, Kuchenbaecker Karoline, Walters Raymond K, Chen Chia-Yen, Popejoy Alice B, Periyasamy Sathish, Lam Max, Iyegbe Conrad, Strawbridge Rona J, Brick Leslie, Carey Caitlin E, Martin Alicia R, Meyers Jacquelyn L, Su Jinni, Chen Junfang, Edwards Alexis C, Kalungi Allan, Koen Nastassja, Majara Lerato, Schwarz Emanuel, Smoller Jordan W, Stahl Eli A, Sullivan Patrick F, Vassos Evangelos, Mowry Bryan, Prieto Miguel L, Cuellar-Barboza Alfredo, Bigdeli Tim B, Edenberg Howard J, Huang Hailiang, Duncan Laramie E
Abstract excerpt
Genome-wide association studies (GWASs) have focused primarily on populations of European descent, but it is essential that diverse populations become better represented. Increasing diversity among study participants will advance our understanding of genetic architecture in all populations and ensure that genetic research is broadly applicable. To facilitate and promote research in multi-ancestry and admixed...
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