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Article

Monogenic susceptibility to live viral vaccines.

Current opinion in immunology - 1 Oct 2021

Gothe Florian, Howarth Sophie, Duncan Christopher Ja, Hambleton Sophie

Abstract excerpt

Live attenuated viral vaccines (LAV) have saved millions of lives globally through their capacity to elicit strong, cross-reactive and enduring adaptive immune responses. However, LAV can also act as a Trojan horse to reveal inborn errors of immunity, thereby highlighting important protective elements of the healthy antiviral immune response. In the following article, we draw out these lessons by reviewing the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34107321
DOI: 10.1016/j.coi.2021.05.006
PMCID: PMC9586878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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