Lessons learned from the study of human inborn errors of innate immunity.

Abstract excerpt

Innate immunity contributes to host defense through all cell types and relies on their shared germline genetic background, whereas adaptive immunity operates through only 3 main cell types, αβ T cells, γδ T cells, and B cells, and relies on their somatic genetic diversification of antigen-specific responses. Human inborn errors of innate immunity often underlie infectious diseases. The range and nature of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Communicable Diseases
• Share to Genetic Diseases, Inborn