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COVID-19 infection in inborn errors of immunity and their phenocopies: a systematic review and meta-analysis.

Infectious diseases (London, England) - 1 Jun 2025

Fekrvand Saba, Saleki Kiarash, Abolhassani Hassan, Almasi-Hashiani Amir, Hakimelahi Ali, Zargarzadeh Nikan, Yekaninejad Mir Saeed, Rezaei Nima

Abstract excerpt

BACKGROUND: Inborn errors of immunity (IEI) are congenital disorders of the immune system. Due to impaired immune system, they are at a higher risk to develop a more severe COVID-19 course compared to general population. OBJECTIVES: Herein, we aimed to systematically review various aspects of IEI patients infected with SARS-CoV-2. Moreover, we performed a meta-analysis to determine the frequency of COVID-19 in...

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PMID: 40178994
DOI: 10.1080/23744235.2025.2483339

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