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Article

Genetic variations in DNA repair gene NEIL1 associated with radiation pneumonitis risk in lung cancer patients.

Molecular genetics & genomic medicine - 1 Jul 2021

Zheng Yuming, Zheng Leizhen, Yu Jiahua, Jiang Mawei, Zhang Songfang, Cai Xuwei, Zhu Meiling

Abstract excerpt

BACKGROUND: Radiation pneumonitis (RP) is a common side effect in lung cancer patients who received radiotherapy. Our previous study found genetic variations in DNA repair gene NEIL1 may be a predictor of RP in patients with esophageal cancer. So, we hypothesis genetic variations in NEIL1 gene could affect the risk of RP in lung cancer patients following radiotherapy. METHODS: Genetic variations rs4462560 G>C and...

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Identifiers

PMID: 34105905
DOI: 10.1002/mgg3.1698
PMCID: PMC8372061

Genes

NEIL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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