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Article

Epigenetic mechanisms underlying prostate cancer radioresistance

8 Jun 2021

Abstract excerpt

Radiotherapy (RT) is one of the mainstay treatments for prostate cancer (PCa), a highly prevalent neoplasm among males worldwide. About 30% of newly diagnosed PCa patients receive RT with a curative intent. However, biochemical relapse occurs in 20-40% of advanced PCa treated with RT either alone or in combination with adjuvant-hormonal therapy. Epigenetic alterations, frequently associated with molecular...

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PMID: 34103085
DOI: 10.1186/s13148-021-01111-8

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