Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mechanism of histone modifications in regulating enzalutamide sensitivity in advanced prostate cancer

13 Apr 2025

Abstract excerpt

Prostate cancer (PCa) is the second most common malignant tumor in men worldwide, particularly castration-resistant prostate cancer (CRPC), for which enzalutamide (Enz) resistance is of particular concern. Modifications to histone methylation and acetylation patterns are closely associated with resistance to Enz in these patients. As PCa progresses, cancer cells alter their histone modification patterns, leading...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Hormonal and reproductive studies
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40303302
DOI: 10.7150/ijbs.109638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mechanism of histone modifications in regulating enzalutamide sensitivity in advanced prostate cancerPMID 40303302Read ↗

Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implicationsSemantic proximity Read ↗

Epigenetic Changes in Prostate Cancer: Implication for Diagnosis and TreatmentSemantic proximity Read ↗

Epigenetics in prostate cancer: clinical implicationsSemantic proximity Read ↗

Epigenetics of prostate cancerSemantic proximity Read ↗

Epigenetic modulators as therapeutic targets in prostate cancerSemantic proximity Read ↗

Enzalutamide-induced signatures revealed by epigenetic plasticity using single-cell multi-omics sequencing in prostate cancerSemantic proximity Read ↗

LncRNA SNHG4 promotes prostate cancer cell survival and resistance to enzalutamide through a let-7a/RREB1 positive feedback loop and a ceRNA networkSemantic proximity Read ↗

Epigenetic mechanisms underlying prostate cancer radioresistanceSemantic proximity Read ↗

Inhibition of enhancer of zeste homolog 2 (EZH2) overcomes enzalutamide resistance in castration-resistant prostate cancerSemantic proximity Read ↗

Inhibition of Galectin-1 and androgen receptor axis enhances enzalutamide treatment in enzalutamide resistant prostate cancerSemantic proximity Read ↗

Epigenetic Regulation in Prostate Cancer ProgressionSemantic proximity Read ↗

Transcriptional and epigenetic reprogramming, lineage plasticity and therapy resistance in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.