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Epigenetic modulators as therapeutic targets in prostate cancer

15 Sept 2016

Abstract excerpt

Prostate cancer is one of the most common non-cutaneous malignancies among men worldwide. Epigenetic aberrations, including changes in DNA methylation patterns and/or histone modifications, are key drivers of prostate carcinogenesis. These epigenetic defects might be due to deregulated function and/or expression of the epigenetic machinery, affecting the expression of several important genes. Remarkably,...

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PMID: 27651838
DOI: 10.1186/s13148-016-0264-8

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