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Regulation of Meiotic Prophase One in Mammalian Oocytes

20 May 2021

Abstract excerpt

In female mammals, meiotic prophase one begins during fetal development. Oocytes transition through the prophase one substages consisting of leptotene, zygotene, and pachytene, and are finally arrested at the diplotene substage, for months in mice and years in humans. After puberty, luteinizing hormone induces ovulation and meiotic resumption in a cohort of oocytes, driving the progression from meiotic prophase...

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Identifiers

PMID: 34095134
DOI: 10.3389/fcell.2021.667306

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